Major pest in the South
Major PGA event
Major piece
Major piece of cribbage equipment
Major pilgrimage destination in Spain
Major pipeline
major player
Major player in international affairs
Major player in the movie biz?
Major player on '70s and '80s TV
Major player?
Major port and commercial and industrial centre on Honshu
Major port in 12-Down
Major port in Iraq
Major port near the Persian Gulf
Major port of Old Rome
Major port of Ukraine
Major port of Yemen
Major port on Osaka Bay
Major port on the Mississippi
Major portion
Major postgrad projects
Major potato producer
Major prank
Major presidential caucus state
Major pro team with the smallest home city
Major problem
Major processing center
major producer of pineapples and bananas
Major producers of oil
Major production
Major prophet
Major protest
major protrusion in bone
Major Publicity
Major publisher of romance novels
Major purchase
Major quinoa exporter
Major race sponsor
Major racket
Major rainfall
Major rant
Major rd.
Major rds.
Major record co.
Major record label
Major record label, once
Major reduction plan
Major region for viticulture
Major region with a minor part?
Major religion
Major religion of Indonesia
Major report
Major residential area
Major responsibility for a parent
Major retail operation
Major retail outlets
Major retailer
Major rift
Major river flowing through Central India
Major river flowing through India
Major river of Pakistan
Major river of Spain
Major river starting in SE Switzerland
Major road
Major road or highway
Major role in "Troy"
Major route
Major routes
Major row
Major rows
Major rte.
Major rtes.
Major Russian river
Major scale that has F as the third note
Major Scandinavian seaport
Major sch. events
Major school assignment
Major science journal
Major Scottish river
Major scrape
Major screw-up
Major screwup
Major scuffle
Major second, e.g.
Major section of a world atlas
Major section of meal
Major section of the "Seventy-Six Trombones" band
Major setback
Major shake-up
Major sheet-metal company
Major shipbuilding city
Major shock
Major shopping centers aren't among the prizes!
Major show
Major showcase
Major sight in the sky?
Major silents star
Major silver exporter
Major ski resort
Major skirmishes
Major sky attraction
Major snag
Major snowslides
Major soccer penalties
Major source for 47 Across: Abbr.
Major source of attar
Major source of Bartlett's quotes
Major source of baseball talent
Major source of coffee beans
Major source of oxygen in the earth's atmosphere
Major source of the narcotic qat
Major source of wheat
Major South Indian river
Major span
Major Spanish port city
Major Spanish river
Major spans
Major speech, as at a convention
Major spring holiday
Major Sri Lankan export
Major star
Major start?
Major starter?
Major steps
Major stir
Major stockholder?
Major stories
Major storm detritus
Major story
Major streaming service
Major street in a minor town
Major street through Yale's campus
Major stretch
Major stretches
Major strikes
Major success
Major success of the dot-com bubble
major successes
Major suffix
major suit
Major suit, briefly
Major supplier of Hiltons
Major supplier to KFC
Major supply
Major supporters of the ACA
Major swag
Major tail?
Major Taiwanese export
Major talent grp. representing athletes and entertainers
Major talking point on CNBC, maybe
Major tanker port
Major tantrum
Major target in Risk
Major tea exporter
Major tea source
Major tech stock
Major telescope maker
Major tenant of Rockefeller Center
Major tennis event
Major tennis tourney
Major tennis tourney, informally
Major test
Major tests
Major Thai export
Major theater chain
Major theme of Philip K. Dick's "Do Androids Dream of Electric Sheep?"
Major thing in the heavens?
major thing in the sky
Major thoroughfare
Major thoroughfares
Major thoroughfares for important traffic
Major time
Major time period
Major time periods
Major time span
Major tin exporter
Major tin producer
Major to-do
Major tourist attraction
Major tourist draw
Major tourist draws
Major tournaments for clergymen?
Major tractor manufacturer
Major transfer spots
Major transition point
Major transportation route
Major transportation routes
Major trial
Major tributary of the Mississippi
Major tributary of the Missouri
Major tributary of the Rhine, flowing through Frankfurt
Major troubles
Major turbulence
Major turf battle
Major Turkish city
Major Tuscan export
Major TV brand
Major TV broadcaster
Major TV logo
Major TV maker
Major TV network
Major U.S. airport
Major U.S. city with three pairs of double letters in its name
Major U.S. lake
Major U.S. network
Major U.S. river
Major U.S./Mexico border crossing
Major UK record label
Major Ukrainian port known as the "Pearl of the Black Sea"
Major under Custer
Major underdog
Major undertaking
Major undertakings
Major unrest
Major upset
Major upset, say
Major urban rd.
Major util.
Major utility pipeline
Major vegetable export of Nigeria (nearly 70% of the world's total)
Major vein
Major vessel
Major vessels
Major video game franchise
Major visibility problem for drivers
Major vitamin retailer
Major water carriers
Major water line
Major water pipe
Major web portal
Major West German port
Major wheat st.
Major with lots of competition, briefly?
Major work
Major work by Virgil
Major work from the Latin for "work"
Major work in grad sch.
Major work of music
Major works
Major World Cup sponsor
Major world power
Major world religion
Major worry
Major wreck
Major-___
Major-___ (bigwig)
Major-___ (chief butler)
Major-__: steward
major-branch-of-mythology